-
Uptake of
oxLDLs causes visible disruption to the
structure of the LSEC in rats.
Doing the same also
damages human LSEC cultures.
Acetyl LDL (ac
LDL) is a...
- used to
detect OxLDL uptake when
OxLDL has been
labeled with 1,1′-dioctadecyl-3,3,3′3′-tetra-methylindocyanide
percholorate (DiI-
OxLDL). Autoimmunity...
-
Oxidized low-density
lipoprotein receptor 1 (
Ox-
LDL receptor 1) also
known as lectin-type
oxidized LDL receptor 1 (LOX-1) is a
protein that in humans...
- Liu LS (January 2012). "PCSK9
siRNA inhibits HUVEC apoptosis induced by
ox-
LDL via Bcl/Bax-caspase9-caspase3 pathway".
Molecular and
Cellular Biochemistry...
-
monoclonal antibody that is used as an anti-inflammatory
agent and
binds to
oxLDL. It acts as an immunomodulator.
World Health Organization (2012). "International...
-
interacts with
lectin type
oxidized LDL receptor-1 (LOX-1)
while its
ligand oxidized low
density lipoprotein (
OxLDL) dis****ociates CCT from LOX-1. The...
- LOX-1 is
primarily known for
binding oxidized low-density
lipoproteins (
oxLDL) but also
binds AGEs. It is
expressed on
endothelial cells,
smooth muscle...
- is
about 80 kDa). It
preferentially binds modified LDL,
either acylated (ac
LDL) or
oxidized (
oxLDL).
Other ligands include: β-amyloid, heat
shock proteins...
-
lipoproteins (i.e.,
oxLDL).
Circulating monocytes attach to the
damaged endothelium, move to the
tunica intima,
ingest the
oxLDL, and
differentiate into...
-
aggregate within the intima. In the
presence of
elevated levels of
oxidized LDL (
ox-
LDL),
monocytes are
converted to
activated macrophages.
Macrophages ac****ulate...
