Definition of Orthosteric. Meaning of Orthosteric. Synonyms of Orthosteric

Here you will find one or more explanations in English for the word Orthosteric. Also in the bottom left of the page several parts of wikipedia pages related to the word Orthosteric and, of course, Orthosteric synonyms and on the right images related to the word Orthosteric.

Definition of Orthosteric

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Meaning of Orthosteric from wikipedia

- or the binding site of the endogenous ligand of a receptor are called orthosteric regulators or modulators. The site to which the effector binds is termed...
- to which an endogenous agonist of the receptor would bind (i.e., an orthosteric site). Modulators and agonists can both be called receptor ligands. Allosteric...
- antagonists, as well as receptor partial agonists, inverse agonists, orthosteric modulators, and allosteric modulators, Examples of receptor modulators...
- and related species of mushroom. Muscimol is a potent and selective orthosteric agonist for the GABAA receptor and displays sedative-hypnotic, depressant...
- Unfortunately the literature often does not distinguish these types properly. Orthosteric agonists and antagonists: bind to the main receptor site (the site where...
- there is no certain treatment for these mental disorders. There is an orthosteric binding site (OBS), as well as a secondary binding pocket (SBP) on the...
- active site inhibitors are known as orthosteric ("regular" orientation) inhibitors. The mechanism of orthosteric inhibition is simply to prevent substrate...
- Activity at GABAA Ligand Orthosteric agonist Muscimol, GABA, gaboxadol (THIP), isoguvacine, progabide, piperidine-4-sulfonic acid (partial agonist) Positive...
- in mice. Docking studies suggest that it fits on both allosteric and orthosteric sites of NMDA receptor. It acts together with other anticholinergic tropane...
- ligands target two different receptor types. Bitopic ligands target an orthosteric binding sites and allosteric binding sites on the same receptor. In scientific...