- is a
Bronsted acid and its
conjugate base, the
orotate anion, is able to bind to metals.
Lithium orotate, for example, has been
investigated for use in...
-
Lithium orotate (C5H3LiN2O4) is a salt of
orotic acid and lithium. It is
available as the monohydrate, LiC5H3N2O4·H2O. In this compound,
lithium is non-covalently...
-
Magnesium orotate, the
magnesium salt of
orotic acid, is a
mineral supplement. It can be used in
treating extracellular magnesium deficiency, as well...
-
Orotate phosphoribosyltransferase (OPRTase) or
orotic acid
phosphoribosyltransferase is an
enzyme involved in
pyrimidine biosynthesis. It
catalyzes the...
- The
enzyme Uridine monophosphate synthase (EC 4.1.1.23, UMPS) (
orotate phosphoribosyl transferase and orotidine-5'-decarboxylase)
catalyses the formation...
-
latter is
converted to
orotate by
dihydroorotate oxidase. The net
reaction is: (S)-Dihydroorotate + O2 →
Orotate + H2O2
Orotate is
covalently linked with...
- In enzymology, an
orotate reductase (NADPH) (EC 1.3.1.15) is an
enzyme that
catalyzes the
chemical reaction (S)-dihydroorotate + NADP+ ⇌ {\displaystyle...
- In enzymology, an
orotate reductase (NADH) (EC 1.3.1.14) is an
enzyme that
catalyzes the
chemical reaction (S)-dihydroorotate + NAD+ ⇌ {\displaystyle...
-
called orotate is
synthesized independently of PRPP.
After orotate is made it is
covalently attached to PRPP. This
results in a
nucleotide called orotate monophosphate...
-
enzymatic step, the ubiquinone-mediated
oxidation of
dihydroorotate to
orotate, in de novo
pyrimidine biosynthesis. This
protein is a
mitochondrial protein...
