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Oritavancin, sold
under the
brand name
Orbactiv (by
Melinta Therapeutics)
among others, is a
semisynthetic glycopeptide antibiotic medication for the...
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Dalbavancin Delafloxacin Fusidic acid
Mupirocin (topical)
Omadacycline Oritavancin Tedizolid Telavancin Tigecycline (also
covers gram negatives) Antibiotics...
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including aminoglycosides, carbapenems, cephalosporins,
daptomycin and
oritavancin.
Enzymes conferring resistance to
fosfomycin have also been identified...
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institutional settings.
Oritavancin was
originally discovered and
developed by Eli Lilly;
Targanta acquired worldwide rights to
oritavancin from
InterMune in...
- have
lipophilic side-chains
linked to glycopeptides. The
class includes oritavancin,
telavancin and dalbavancin. In
September 2009 the US Food and Drug Administration...
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semisynthetic second generation includes lipoglycopeptides like telavancin,
oritavancin and dalbavancin. The
extra lipophilicity not only
enhances Lipid II binding...
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often used as off-label
salvage therapy in
systemic VRE
infections is
oritavancin, a
semisynthetic glycopeptide that has
demonstrated synergic activity...
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strains vancomycin cannot bind,
because a
crucial hydrogen bond is lost.
Oritavancin also uses the D-Ala-D-Ala terminus, but in
addition it uses the crossbridge...
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seven years. The
cephalosporin ceftaroline and the
lipoglycopeptides oritavancin and
telavancin have been
approved for the
treatment of
acute bacterial...
- and
aliphatic tails. It is part of the
active group in the
antibiotic oritavancin.
Biphenyl prevents the
growth of
molds and fungus, and is
therefore used...