-
Optineurin is a
protein that in
humans is
encoded by the OPTN gene. This gene
encodes the coiled-coil
containing protein optineurin.
Optineurin may play...
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Variant of
Optineurin, M98K,
Activates Tbk1 to
Enhance Autophagosome Formation and
Retinal Cell
Death Dependent on Ser177
Phosphorylation of
Optineurin". PLOS...
- OPTN may
refer to:
Optineurin Organ Procurement and
Transplantation Network,
operated by the
United Network for
Organ Sharing,
which facilitates organ...
-
through the
attachment of
Ubiquitin and
finally the
phosphorylating protein optineurin binds to them. This tags them for
special cell organelles, the autophagosomes...
- et al. (2007). "SNPs and
interaction analyses of
noelin 2, myocilin, and
optineurin genes in ****anese
patients with open-angle glaucoma". Invest. Ophthalmol...
- to do any
physical activity due to the
atrophy of
their muscles. The
optineurin gene (OPTN) and its
mutation are
known to be
involved in ALS. When the...
-
protein production. This
results in no
phosphorylation of the p62 and
optineurin proteins. As a result,
motor neurons can no
longer produce a functional...
-
Suzanne R (eds.). "Degradation of
engulfed mitochondria is rate-limiting in
Optineurin-mediated
mitophagy in neurons". eLife. 9: e50260. doi:10.7554/eLife.50260...
- to MY09B on
chromosome 19p13.1. RAB8A has been
shown to
interact with
Optineurin and MAP4K2. GRCh38:
Ensembl release 89: ENSG00000167461 – Ensembl, May...
- Cell Biol, doi:10.1038/s41556-021-00672-3 (2021). Du, W. et al. Loss of
optineurin drives cancer immune evasion via palmitoylation-dependent IFNGR1 lysosomal...
