-
Opioids are a
class of
drugs that
derive from, or mimic,
natural substances found in the
opium poppy plant.
Opioids work in the
brain to
produce a variety...
- The
opioid epidemic, also
referred to as the
opioid crisis, is the
rapid increase in the overuse, misuse/abuse, and
overdose deaths attributed either...
- An
opioid antagonist, or
opioid receptor antagonist, is a
receptor antagonist that acts on one or more of the
opioid receptors.
Naloxone and naltrexone...
-
Opioid receptors are a
group of
inhibitory G protein-coupled
receptors with
opioids as ligands. The
endogenous opioids are dynorphins, enkephalins, endorphins...
- The μ-
opioid receptors (MOR) are a
class of
opioid receptors with a high
affinity for
enkephalins and beta-endorphin, but a low
affinity for dynorphins...
-
Opioid use
disorder (OUD) is a
substance use
disorder characterized by
cravings for
opioids,
continued use
despite physical and/or
psychological deterioration...
- An
opioid overdose is
toxicity due to
excessive consumption of
opioids, such as morphine, codeine, heroin, fentanyl, tramadol, and methadone. This preventable...
-
Opioid withdrawal is a set of
symptoms (a syndrome)
arising from the
sudden cessation or
reduction of
opioids where previous usage has been
heavy and...
-
There is an
ongoing opioid epidemic (also
known as the
opioid crisis) in the
United States,
originating out of both
medical prescriptions and illegal...
- The κ-
opioid receptor or
kappa opioid receptor,
abbreviated KOR or KOP for its
ligand ketazocine, is a G protein-coupled
receptor that in
humans is encoded...
