- An
oncomir (also
oncomiR) is a
microRNA (miRNA) that is ****ociated with cancer.
MicroRNAs are
short RNA
molecules about 22
nucleotides in length. Essentially...
-
expression by
downregulating them.
Mutations in such
microRNAs (known as
oncomirs) can lead to
activation of oncogenes.
Antisense messenger RNAs
could theoretically...
- PTEN is
inhibited by sarcopoterium. PTEN is one of the
targets of the
oncomiR, MIRN21. Cell
lines with
known PTEN
mutations include: prostate: LNCaP...
-
abnormalities in the
heart and
vascular system. It is one of the
targets of an
oncomiR, MIRN21. In
humans mutations of this gene
result in
autosomal dominant...
- in
humans is
encoded by the PDCD4 gene. It is one of the
targets of an
oncomiR, MIRN21. This gene
encodes a
protein localized to the
nucleus in proliferating...
- also have
links with
cancer and
accordingly are
sometimes referred to as "
oncomirs". In
malignant B
cells miRNAs parti****te in
pathways fundamental to B...
-
production and lifespan, and the up-regulation and down-regulation of
oncomirs.
Given their role in presentation, HSPs are
useful as
immunologic adjuvants...
- PMID 18508928. Medina,
Pedro P.; Nolde, Mona; Slack,
Frank J. (September 2010). "
OncomiR addiction in an in vivo
model of microRNA-21-induced pre-B-cell lymphoma"...
- in
humans is
encoded by the ANP32A gene. It is one of the
targets of an
oncomiR, MIRN21.
Acidic leucine-rich
nuclear phosphoprotein 32
family member A...
- Li Y, Gu H, Liu MF, Wang ED (Apr 2010). "MicroRNA-155
functions as an
OncomiR in
breast cancer by
targeting the
suppressor of
cytokine signaling 1 gene"...
