- An
oncogene is a gene that has the
potential to
cause cancer. In
tumor cells,
these genes are
often mutated, or
expressed at high levels. Most
normal cells...
-
Oncogene addiction is a
process in
which cancers with genetic, epigenetic, or
chromosomal irregularities become dependent on one or
several genes for maintenance...
- Myc is a
family of
regulator genes and proto-
oncogenes that code for
transcription factors. The Myc
family consists of
three related human genes: c-myc...
-
Oncogene is a peer-reviewed
scientific journal published under the
Springer Nature addressing cancer cell
genetics and the
structure and
function of oncogenes...
- into the host cell or to
enhance already existing oncogenic genes (proto-
oncogenes) in the genome. For example, it has been
shown that
vFLIP and vCyclin...
- Proto-
oncogene c-KIT is the gene
encoding the
receptor tyrosine kinase protein known as tyrosine-protein
kinase KIT, CD117 (cluster of differentiation...
- Tpr-Met
fusion protein is an
oncogene fusion protein consisting of TPR and MET. Tpr-Met was
generated following a
chromosomal rearrangement induced by...
- BOC
Identifiers Aliases BOC, CDON2, BOC cell
adhesion ****ociated,
oncogene regulated, Boi
External IDs OMIM: 608708; MGI: 2151153; HomoloGene: 32819; GeneCards:...
-
initially isolated from the
Abelson murine leukemia virus. The ABL1 proto-
oncogene encodes a
cytoplasmic and
nuclear protein tyrosine kinase that has been...
-
produce a
functional fusion protein. Many
important cancer-promoting
oncogenes are
fusion genes produced in this way.
Examples include: Gag-onc fusion...
