-
Olorofim (F901318) is an
experimental antifungal drug
being developed for
invasive mold infections. If
approved it
would be a first-in-class medication...
-
October 2021). "The
Antifungal Pipeline: Fosmanogepix, Ibrexafungerp,
Olorofim, Opelconazole, and Rezafungin". Drugs. 81 (15): 1703–1729. doi:10.1007/s40265-021-01611-0...
- (October 2021). "The
Antifungal Pipeline: Fosmanogepix, Ibrexafungerp,
Olorofim, Opelconazole, and Rezafungin". Drugs. 81 (15): 1703–1729. doi:10.1007/s40265-021-01611-0...
-
orotic acid.
Brequinar Teriflunomide Leflunomide S416
Vidofludimus Calcium Olorofim Orludodstat The
immunomodulatory drugs teriflunomide and
leflunomide have...
- (October 2021). "The
Antifungal Pipeline: Fosmanogepix, Ibrexafungerp,
Olorofim, Opelconazole, and Rezafungin". Drugs. 81 (15): 1703–1729. doi:10.1007/s40265-021-01611-0...
-
Aspergillus and
other deadly moulds are the
basis for at
least one new therapy,
Olorofim,
which is
currently in
phase 2b
clinical trials and has
received breakthrough...
- n-2-yl)piperazin-1-yl]-phenyl}-2-oxo-acetamide. F901318 has been
named Olorofim.
Unlike other antifungal drugs, the
orotomides act
differently by stopping...
-
vitro efficacy as
treatment for
scedosporiosis (including S. prolificans).
Olorofim, a new
dihydroorotate dehydrogenase inhibitor –
which disrupts pyrimidine...
