-
Obtusifoliol is a
metabolic intermediate of
sterols made by
certain fungi. It can be
converted to delta8,14-sterol by the
enzyme ERG11 (CYP51F1). Park...
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member of the CYP51 family. It
catalyzes a
chemical reaction such as:
obtusifoliol + 3 O2 + 3
NADPH + 3 H+ ⇌ {\displaystyle \rightleftharpoons }...
- (SQE),
cycloartenol synthase (CAS),
sterol methyl transferase (SMT),
obtusifoliol-14 –demethylase (ODM). To
produce withaferin A from 24-methylene cholesterol...
- Friedelin, a
triterpene Isoarborinol Lanosterol, a
tetracyclic triterpenoid Obtusifoliol Lupeol 2,3-Oxidosqualene
Parkeol Taraxasterol Taraxerol This set index...
- {\displaystyle \rightleftharpoons }
obtusifoliol Hence, this
enzyme has one substrate, cycloeucalenol, and one product,
obtusifoliol. This
enzyme belongs to the...
-
sterol biosynthesis in higher-plants by
inhibiting the cycloeucalenol-
obtusifoliol isomerase. This
inhibition was
shown to not only
alter the
lipid composition...
- (February 1997). "Cloning and
expression in
Escherichia coli of the
obtusifoliol 14 alpha-demethylase of
Sorghum bicolor (L.) Moench, a
cytochrome P450...
- (February 1997). "Cloning and
expression in
Escherichia coli of the
obtusifoliol 14 alpha-demethylase of
Sorghum bicolor (L.) Moench, a
cytochrome P450...
-
mammal or
yeast cytochrome P450
sterol 14alpha-demethylase.
Lanosterol Obtusifoliol Cycloartenol Lepesheva, GI; Waterman, MR (March 2007). "Sterol 14alpha-demethylase...