-
Francisella novicida is a
bacterium of the
Francisellaceae family,
which consist of Gram-negative
pathogenic bacteria.
These bacteria vary from
small cocci...
- species, F. tularensis,
causes the
disease tularemia or
rabbit fever. F.
novicida and F.
philomiragia (previously
Yersinia philomiragia) are ****ociated with...
-
ability to
infect humans. Additionally, F.
novicida has
sometimes previously been
classified as F. t.
novicida. It was
characterized as a
relatively nonvirulent...
- to edit
genes at any
desired genome location. The Cas9 of
Francisella novicida recognizes the
canonical PAM
sequence 5'-NGG-3', but has been engineered...
- 2011.
Whipp MJ;
Davis JM; Lum G; et al. (2003). "Characterization of a
novicida-like
subspecies of
Francisella tularensis isolated in Australia". Journal...
- was
characterized in the CRISPR-Cpf1
system of the
bacterium Francisella novicida. Its
original name, from a
TIGRFAMs protein family definition built in...
-
pyrin and ZBP1 to
promote PANoptosis and host
defense in
response to F.
novicida and HSV1. Like AIM2, IFI16 (IFN-inducible
protein 16)
belongs to the PYHIN...
-
includes the AIM2 inflammasome, and ****embles in
response to
Francisella novicida and
herpes simplex virus 1 (HSV1) infections. ZBP1 has also been extensively...
- RIPK3, and RIPK1 in
response to
specific pathogens,
including Francisella novicida and
herpes simplex virus 1 (HSV1), to
drive PANoptosis.
Regulation of inflammasome...
-
bacterium ability to
induce disease in a
mouse model. A
major study in F. t.
novicida later demonstrated FtrA to be ****ociated with a CRISPR/Cas
system and to...
