-
Higenamine (
norcoclaurine) is a
chemical compound found in a
variety of
plants including Nandina domestica (fruit),
Aconitum carmichaelii (root), Asarum...
- The
enzyme (S)-
norcoclaurine synthase (EC 4.2.1.78)
catalyzes the
chemical reaction 4-hydroxyphenylacetaldehyde + 4-(2-aminoethyl)benzene-1,2-diol (Dopamine)...
-
comprehensively discussed by Hagel. The
biosynthesis of (S)-
norcoclaurine,
which is
catalyzed by (S)-
norcoclaurine synthase, is
accomplished by the stereoselective...
- (RS)-
norcoclaurine 6-O-methyltransferase (EC 2.1.1.128) is an
enzyme that
catalyzes the
chemical reaction S-adenosyl-L-methionine + (RS)-
norcoclaurine ⇌...
-
tetrahydroisoquinoline instead of the dihydroisoquinoline. In enzymology, the (S)-
norcoclaurine synthase (EC 4.2.1.78) is an
enzyme that
catalyzes a
biological Pictect-Spengler...
- form dopamine.
Norcoclaurine synthase (NCS)
catalyzes a Pictet-Spengler
reaction between 4-HPAA and
dopamine to
synthesize (S)-
norcoclaurine,
providing the...
- miquelianin, as well as the
alkaloids (+)-(1R)-coclaurine and (−)-(1S)-
norcoclaurine, can be
found in the
leaves of N. nucifera. The
plant also contains...
- L-DOPA
reacts with 4-HPAA and,
through a
series of reactions,
forms (S) -
norcoclaurine,
which carries the
benzylisoquinoline skeleton that
gives its name to...
- 4-hydroxyphenyl-acetaldehyde and dopamine.
These two
compounds are
combined to form
norcoclaurine. Next,
methyl groups are
added to form N-methylcoclaurine. The enzyme...
-
Condensation of
these precursors yields the
primary intermediate higenamine (
norcoclaurine).
Subsequent action of four
enzymes yields the tetrahydroisoquinoline...
