-
Norbuprenorphine is a
major active metabolite of the
opioid modulator buprenorphine. It is a μ-opioid, δ-opioid, and
nociceptin receptor full agonist,...
-
brain penetration of
norbuprenorphine due to a high
affinity of the
compound for P-glycoprotein. In
contrast to
norbuprenorphine,
buprenorphine and its...
-
Norbuprenorphine-3-glucuronide (N3G) is a
major active metabolite of the
opioid modulator buprenorphine. It has
affinity for the κ-opioid
receptor (Ki...
- liver,
primarily via the
cytochrome P450 (CYP)
isozyme CYP3A4, into
norbuprenorphine. The
glucuronidation of
buprenorphine is
primarily carried out by the...
- most
similar to the
parent drug.
Unlike norbuprenorphine, but
similarly to
buprenorphine (and
norbuprenorphine-3-glucuronide), B3G is not a
substrate for...
- blood-brain-barrier and thus
central nervous system penetration.
Norbuprenorphine Norbuprenorphine-3-glucuronide
Normorphine Noroxymorphone Zhou S (6
April 2016)...
-
Nalodeine (N-allylnorcodeine)
Nalorphine Naltriben Niravoline Norbuprenorphine Norbuprenorphine-3-glucuronide
Noribogaine Norketamine Oripavine Oxilorphan...
-
Nalodeine (N-allylnorcodeine)
Nalorphine Naltriben Niravoline Norbuprenorphine Norbuprenorphine-3-glucuronide
Noribogaine Norketamine Oripavine Oxilorphan...
-
intermediate in the
creation of
hydromorphone Hydromorphone Oxycodone Norbuprenorphine Norbinaltorphimine Lemberg KK,
Siiskonen AO,
Kontinen VK, Yli-Kauhaluoma...
- N-cyclopropylmethylnoretorphine [44] Nepenthone [45] [46]
Norbuprenorphine Norbuprenorphine-3-glucuronide Thevinone [47]
Thienorphine [48] TH-030418 Structures...
