-
Nocodazole is an
antineoplastic agent which exerts its
effect in
cells by
interfering with the
polymerization of microtubules.
Microtubules are one type...
- metaphase-to-anaphase
transition in
response to the
microtubule poison nocodazole.
Subsequent cloning of the
Xenopus laevis orthologue,
facilitated by the...
-
dividing cells.
Cells will
remain arrested until the
nocodazole has been
washed out.
Nocodazole does not
appear to
disrupt interphase metabolism, and...
- cell
cycle again.
Nocodazole is a
chemical agent that
interferes with the
polymerization of microtubules.
Cells treated with
nocodazole arrest with a G2...
- a
cancer treatment. Ivermectin –
Medication for
parasite infestations Nocodazole –
Microtubule depolymerizing drug Praziquantel – Anti-parasite medication...
-
Wadsworth P, C****imeris L (June 1997). "Nanomolar
concentrations of
nocodazole alter microtubule dynamic instability in vivo and in vitro". Molecular...
-
mechanism exists at the metaphase-to-anaphase transition.
Using drugs such as
nocodazole and colchicine, the
mitotic spindle dis****embles and the cell
cycle is...
-
removed from the
culture and the
cells then
begin to grow synchronously.
Nocodazole, for example, has been used in
biological research for synchronization...
- e.g. Ixabepilone, work in a
similar way to the taxanes. Vinorelbine,
Nocodazole, vincristine, and
colchicine have the
opposite effect,
blocking the polymerization...
- cycles. Microtubule-disruptive
drugs like vinblastine, colcemid, and
nocodazole have been
reported to act by two mechanisms. At very low concentrations...
