- N-Nitroso-N-methylurea
Nimustine Ranimustine Semustine Streptozocin Some
nitrosoureas (e.g. lomustine) have been ****ociated with the
development of interstitial...
-
Ifosfamide Lomustine Melphalan Melphalan flufenamide Mitobronitol Nimustine Nitrosoureas Pipobroman Ranimustine Semustine Streptozotocin Temozolomide Thiotepa...
- led by John
Montgomery at the
Southern Research Institute,
synthesized nitrosoureas, an
alkylating agent which cross-links DNA.
Fludarabine phosphate, a...
-
medication used
mainly for chemotherapy. It is a
nitrogen mustard β-chloro-
nitrosourea compound used as an
alkylating agent.
Carmustine is an orange-yellow...
- ENU, also
known as N-ethyl-N-
nitrosourea (chemical
formula C3H7N3O2), is a
highly potent mutagen. For a
given gene in mice, ENU can
induce 1 new mutation...
-
ability to
created interstrand cross-links (ICLs) in DNA. As with
other nitrosoureas, it may also
inhibit several key
enzymatic processes by carbamoylation...
-
similar functional group.
Specific classes include the N-nitrosamides, N-
nitrosoureas, N-nitrosoguanidines, and N-nitrosocarbamates.
Nitrosamides are usually...
- of drug. The
subtypes of
alkylating agents are the
nitrogen mustards,
nitrosoureas, tetrazines, aziridines,
cisplatins and derivatives, and non-classical...
- that its
advantages over
other nitrosoureas are a
relatively low
hematological toxicity (compared to
other nitrosoureas available at that time) and a wider...
- are "nitrogen mustards, oxazaphosphorines,
alkyl alkane, sulphonates,
nitrosoureas,
tetrazines and aziridines."
Malignancy has been a
constant global health...
