-
Methylnitronitrosoguanidine (MNNG or MNG, NTG when
referred to
colloquially as
nitrosoguanidine) is a
biochemical tool used
experimentally as a
carcinogen and mutagen...
- group.
Specific classes include the N-nitrosamides, N-nitrosoureas, N-
nitrosoguanidines, and N-nitrosocarbamates.
Nitrosamides are
usually chemically reactive...
-
compared to
reagents like N-methyl-N-nitrosourea and N-methyl-N'-nitro-N-
nitrosoguanidine,
which are less
thermally stable and more
toxic and mutagenic, respectively...
-
Bader and Jack
Eisendrath and
manufactured just 1-methyl-3-nitro-1-
nitrosoguanidine. 1966 – Aldrich's IPO 1972 –
Subsidiary Aldrich-Boranes
launched to...
- incorrect. The
three letters of MET come from N-methyl-N'-nitro-N-
nitrosoguanidine (MNNG).
Abnormal MET
activation in
cancer correlates with poor prognosis...
-
localized point mutations,
examples of such
chemicals are aminopurine,
nitrosoguanidine, and bisulfite. Site-directed
mutagenesis was
achieved in 1974 in the...
-
Methyl methanesulfonate Mercaptobenzothiozole MNNG (N-Methyl-N'-nitro-N-
nitrosoguanidine) N-Methyl-N-nitrosourea
Nitrate or
nitrite (ingested)
under conditions...
- been
largely surp****ed by more
potent mutagens such as EMS, ENU, or
nitrosoguanidine, but
being a very
small mutagenic compound with high specificity, it...
- decay,
psoralen plus near-UV
irradiation (PUVA), N-methyl-N'-nitro-N-
nitrosoguanidine (MNNG),
methyl methane sulfonate (MMS) and
nitrous acid.
Several of...
- dinotefuran, imidacloprid, and thiamethoxam. The
nitrosoylated derivative,
nitrosoguanidine, is
often used to
mutagenize bacterial cells for
biochemical studies...
