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Nitroreductases are a
family of
evolutionarily related proteins involved in the
reduction of nitrogen-containing compounds,
including those containing...
- anti-cancer gene therapy.
There are at
least two oxygen-insensitive
nitroreductases in E. coli. The
major one is NfsA (P17117, EC 1.7.1.B3). The other...
- (January 2012). "Activation of
benznidazole by
trypanosomal type I
nitroreductases results in
glyoxal formation".
Antimicrobial Agents and Chemotherapy...
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plants enzymes such as peroxidases, phenoloxidases,
esterases and
nitroreductases carry out the same role. In the
second stage of phytotransformation...
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prosthetic group found in,
among other proteins, NADH dehydrogenase, E.coli
nitroreductase and old
yellow enzyme.
Pteridine Pterin Deazaflavin (5-deazaflavin)...
- Wang AH, Peng FC (July 2009). "Characterization of
Escherichia coli
nitroreductase NfsB in the
metabolism of nitrobenzodiazepines".
Biochemical Pharmacology...
-
metabolites are key
mediators of CB 1954 and SN 23862
bystander effects in
nitroreductase GDEPT".
British Journal of Cancer. 90 (5): 1084–1092. doi:10.1038/SJ...
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Pretomanid is
activated in the
mycobacterium by deazaflavin-dependent
nitroreductase (Ddn), an
enzyme which uses dihydro-F420 (reduced form), into nitric...
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genus of Streptomyces.
Streptomyces mirabilis produces miramycin and
nitroreductase.
Streptomyces mirabilis has a very high
resistance against nickel. List...
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Delamanid is
activated in the
mycobacterium by deazaflavin-dependent
nitroreductase (Ddn), an
enzyme which uses dihydro-F420 (reduced form), into nitric...