- megazol, and azanidazole.
Drugs based on 2-
nitroimidazoles include benznidazole and azomycin.
Nitroimidazole antibiotics have been used to
combat anaerobic...
- p. 356. ISBN 978-1-4557-4801-3.
Wilcox MH (January 2017), "147 -
Nitroimidazoles, Metronidazole,
Ornidazole and Tinidazole; and Fidaxomicin", in Cohen...
-
metronidazole as an
adjuvant agent in
radiation therapy. However,
other nitroimidazoles derived from
metronidazole such as
nimorazole with
reduced electron...
-
potential and so will not
reduce nitroimidazoles to the
radical form. This
limits the
spectrum of
activity of
nitroimidazoles so that host
cells and DNA are...
- 2-
nitroimidazole nitrohydrolase (EC 3.5.99.9, NnhA, 2NI nitrohydrolase, 2NI denitrase) is an
enzyme with
systematic name 2-
nitroimidazole nitrohydrolase...
- infections. It was
developed in 1972 and is a
prominent member of the
nitroimidazole antibiotic class. It is on the
World Health Organization's List of Essential...
-
acquired Searle and SUGEN.
Searle had
developed Flagyl (metronidazole), a
nitroimidazole antibiotic medication used
particularly for
anaerobic bacteria and protozoa...
-
levels (hypoxia) in tumors,
which can
hinder radiation effectiveness.
Nitroimidazoles:
Mimic oxygen,
enhancing free
radical formation in
hypoxic cells. Oxygen...
-
Other names Metronidazole-OH; 1-(2-Hydroxyethyl)-2-hydroxymethyl-5-
nitroimidazole Identifiers CAS
Number 4812-40-2 Y 3D
model (JSmol)
Interactive image...
- ATC code P01
Antiprotozoals is a
therapeutic subgroup of the
Anatomical Therapeutic Chemical classification System, a
system of
alphanumeric codes developed...