-
Nirogacestat, sold
under the
brand name Ogsiveo, is an anti-cancer
medication used for the
treatment of
desmoid tumors. It is a
selective gamma secretase...
-
nipradilol (INN)
Nipride niprofazone (INN)
niravoline (INN)
niridazole (INN)
nirogacestat (INN)
nisbuterol (INN)
nisobamate (INN)
nisoldipine (INN) nisoxetine...
-
required for
local symptoms, the risk of
recurrence appears to be lower.
Nirogacestat, a
selective gamma secretase inhibitor, was
approved for
medical use...
- Network. The
Desmoid Tumor Research Foundation helped spearhead trials of
nirogacestat for use in
desmoid patients. Its
advocacy led to the
creation of desmoid-specific...
- own and in
conjunction with the
selective gamma secretase inhibitor nirogacestat. GRCh38:
Ensembl release 89: ENSG00000048462 – Ensembl, May 2017 GRCm38:...
- and 49 (epsilon-cleavage). DAPT (chemical), a γ-secretase
inhibitor Nirogacestat, a γ-secretase
inhibitor Semagacestat, a γ-secretase
inhibitor Bai, Xiao-chen;...
- for its
Phase 1/2a study,
which features PBCAR269A in
combination with
nirogacestat, a
gamma secretase inhibitor. In 2020, the FDA
granted fast
track designation...
