-
Nilutamide, sold
under the
brand names Nilandron and Anandron, is a
nonsteroidal antiandrogen (NSAA)
which is used in the
treatment of
prostate cancer...
-
largely replaced the
earlier nonsteroidal antiandrogens flutamide and
nilutamide,
which are now
little used. The
earlier androgen synthesis inhibitors...
- or
other first-generation
NSAAs (i.e.,
flutamide and
nilutamide). A m****ive
overdose of
nilutamide (13 grams, or 43
times the
normal maximum 300 mg/day...
- parameters.
Relative to the
other first-generation NSAAs,
flutamide and
nilutamide,
bicalutamide shows improved potency, efficacy, tolerability, and safety...
- ****ociated side
effect of
certain drugs such as disulfiram, metronidazole, or
nilutamide. Skin
flushing and
nasal congestion are the most
common symptoms of intolerance...
-
different side-chain.
These compounds are
similar in
chemical structure to
nilutamide,
which is
related to flutamide, bicalutamide, and enzalutamide, all of...
-
comparison to first-generation
NSAAs such as bicalutamide, flutamide, and
nilutamide. Also,
unlike with the first-generation NSAAs,
there has been no evidence...
- first-generation NSAA
nilutamide and by
extension from flutamide.
Chemical structures of
apalutamide and its
predecessors Flutamide Nilutamide RU-59063 Enzalutamide...
- are 5 to 20% for flutamide, 2 to 5% for bicalutamide, and 2 to 4% for
nilutamide. In
contrast to diarrhea, the
rates of
nausea and
vomiting are similar...
-
treatment of
prostate cancer. In 1995,
bicalutamide was approved, and
nilutamide followed a year later. The AR
belongs to the
steroid receptor subfamily...
