-
glycosylated receptors that can bind to
neurotrophins.
These two
proteins are p75 (NTR),
which binds to all
neurotrophins, and
subtypes of Trk,
which are each...
-
other neurotrophins equally well as
nerve growth factor. p75NTR is a
neurotrophic factor receptor.
Neurotrophic factor receptors bind
Neurotrophins including...
- is a
neurotrophic factor in the NGF (Nerve
Growth Factor)
family of
neurotrophins. It is a
protein growth factor which has
activity on
certain neurons...
- J, et al. (February 1993). "Similarities and
differences in the way
neurotrophins interact with the Trk
receptors in
neuronal and
nonneuronal cells"....
- axons. Most
neurotrophic factors belong to one of
three families: (1)
neurotrophins, (2)
glial cell-line
derived neurotrophic factor family ligands (GFLs)...
- only bind with
specific neurotrophins, but with a much
higher affinity. The Trks
mediate the
functional signals of the
neurotrophins. NGF
binds to TrkA, BDNF...
- main
causes of
neurodegeneration involves changes in the
expression of
neurotrophins (NTs) and/or
their receptors (TrkA, TrkB, TrkC and p75NTR). Indeed,...
- DHEA-S,
directly bind to and
activate TrkA and p75NTR,
receptors of
neurotrophins like
nerve growth factor (NGF) and brain-derived
neurotrophic factor...
-
neurons from
neural stem
cells in a
process known as neurogenesis.
Neurotrophins are
proteins that help to
stimulate and
control neurogenesis, BDNF being...
- cleavage.
Immature neurotrophins are
specific only to one
common p75NTR receptor. However,
protease cleavage generates neurotrophins that have
higher affinity...