-
Neurotrophins are a
family of
proteins that
induce the survival, development, and
function of neurons. They
belong to a
class of
growth factors, secreted...
- The p75
neurotrophin receptor (p75NTR) was
first identified in 1973 as the low-affinity
nerve growth factor receptor (LNGFR)
before discovery that p75NTR...
-
Neurotrophin-4 (NT-4), also
known as
neurotrophin-5 (NT-5), is a
protein that in
humans is
encoded by the NTF4 gene. It is a
neurotrophic factor that...
-
Neurotrophin-3 is a
protein that in
humans is
encoded by the NTF3 gene. The
protein encoded by this gene, NT-3, is a
neurotrophic factor in the NGF (Nerve...
- the
neurotrophin receptors from
early on in the
evolution of the
nervous system. The
findings that DHEA
binds to and
potently activates neurotrophin receptors...
-
Neurotrophin mimetics are
small molecules or
peptide like
molecules that can
modulate the
action of the
neurotrophin receptor. One of the main
causes of...
- gene. TrkC is the high
affinity catalytic receptor for the
neurotrophin NT-3 (
neurotrophin-3). As such, TrkC
mediates the
multiple effects of this neurotrophic...
- axons. Most
neurotrophic factors belong to one of
three families: (1)
neurotrophins, (2)
glial cell-line
derived neurotrophic factor family ligands (GFLs)...
-
Neurotrophic factor receptors or
neurotrophin receptors are a
group of
growth factor receptors which specifically bind to
neurotrophins (neurotrophic factors)....
- that, in humans, is
encoded by the BDNF gene. BDNF is a
member of the
neurotrophin family of
growth factors,
which are
related to the
canonical nerve growth...
