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Neurotensin is a 13
amino acid
neuropeptide that is
implicated in the
regulation of
luteinizing hormone and
prolactin release and has
significant interaction...
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Neurotensin receptors are
transmembrane receptors that bind the
neurotransmitter neurotensin. Two of the
receptors encoded by the NTSR1 and NTSR2 genes...
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Neurotensin receptor type 1 is a
protein that in
humans is
encoded by the NTSR1 gene. For a
crystal structure of NTS1, see pdb code 4GRV. In addition...
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Neurotensin receptor type 2 is a
protein that in
humans is
encoded by the NTSR2 gene. The
protein encoded by this gene
belongs to the G protein-coupled...
- tract.
Hormones secreted include somatostatin, motilin, cholecystokinin,
neurotensin,
vasoactive intestinal peptide, and enteroglucagon. The enteroendocrine...
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selective antagonist for the
neurotensin receptor NTS2, and was the
first drug used to
characterise the
different neurotensin subtypes. This has made it...
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Crystallization studies of the
protein reveal that, when
complexed with the
ligand neurotensin, the Vps10
ectodomain of
sortilin forms a ten-bladed beta-propeller structure...
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Neurolysin (EC 3.4.24.16,
neurotensin endopeptidase,
endopeptidase 24.16, endo-oligopeptidase B (proline-endopeptidase)) is an enzyme. This
enzyme catalyses...
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paracrine effect. Some
notable autacoids are: eicosanoids, angiotensin,
neurotensin, NO (nitric oxide), kinins, histamine, serotonin,
endothelins and palmitoylethanolamide...
- (SR-48692) is a drug
which acts as a selective, non-peptide
antagonist at the
neurotensin receptor NTS1, and was the
first non-peptide
antagonist developed for...
