Definition of Neoantigens. Meaning of Neoantigens. Synonyms of Neoantigens

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Definition of Neoantigens

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Meaning of Neoantigens from wikipedia

- attack. Neoantigens are those that are entirely absent from the normal human genome. As compared with nonmutated self-proteins, neoantigens are of relevance...
- "nonself" tumor-specific mutant antigens (neoantigens). Sequencing and epitope prediction algorithms identified neoantigens in mouse tumors that functioned as...
- an epitope on a neoantigen, which is a newly formed antigen that has not been previously recognized by the immune system. Neoantigens are often ****ociated...
- pattern of tumor-specific mutated peptides referred to as neoantigens or m-peptides. Neoantigens are products of mutations that first occur in the course...
- individualised neoantigen-specific immunotherapy containing multiple different mRNA species that together encode up to 20 neoantigens that have been identified...
- estimator of neoantigen load and can help find the patients who can benefit from ICI therapy by increasing the chance of detecting the neoantigens. However...
- mutations. These mutations potentially create new targetable antigens (neoantigens) for use in T-cell immunotherapy. The presence of CD8+ T cells in cancer...
- peptides. A requirement for the recognition of neoantigens by the immune system is that the neoantigens and their antigenic determinants, the neoepitopes...
- result in the production of aberrant proteins that can be recognized as neoantigens by the immune system, particularly in cancer cells. However, frameshift...
- (MHC) bounded peptides. They represent the antigenic determinants of neoantigens. Neoepitopes are recognized by the immune system as targets for T cells...