Definition of Neoantigen. Meaning of Neoantigen. Synonyms of Neoantigen

- Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful tumor markers...
- attack. Neoantigens are those that are entirely absent from the normal human genome. As compared with nonmutated self-proteins, neoantigens are of relevance...
- an epitope on a neoantigen, which is a newly formed antigen that has not been previously recognized by the immune system. Neoantigens are often ****ociated...
- peptides. A requirement for the recognition of neoantigens by the immune system is that the neoantigens and their antigenic determinants, the neoepitopes...
- individualised neoantigen-specific immunotherapy containing multiple different mRNA species that together encode up to 20 neoantigens that have been identified...
- (MHC) bounded peptides. They represent the antigenic determinants of neoantigens. Neoepitopes are recognized by the immune system as targets for T cells...
- There he led the development of NeoVax, a first-in-class personalized neoantigen cancer vaccine through IND approval and successful execution of two clinical...
- "nonself" tumor-specific mutant antigens (neoantigens). Sequencing and epitope prediction algorithms identified neoantigens in mouse tumors that functioned as...
- vaccination generates an immune response which increases the number of neoantigen-specific T cells in the body and that Olvi-Vec induces an acute inflammatory...
- estimator of neoantigen load and can help find the patients who can benefit from ICI therapy by increasing the chance of detecting the neoantigens. However...