Definition of Neoantigen. Meaning of Neoantigen. Synonyms of Neoantigen

- Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful tumor markers...
- attack. Neoantigens are those that are entirely absent from the normal human genome. As compared with nonmutated self-proteins, neoantigens are of relevance...
- individualised neoantigen-specific immunotherapy containing multiple different mRNA species that together encode up to 20 neoantigens that have been identified...
- an epitope on a neoantigen, which is a newly formed antigen that has not been previously recognized by the immune system. Neoantigens are often ****ociated...
- studies how to implement personalized cancer vaccines by identifying neoantigen targets created by a patient's tumor. In 2023, Wu was elected a fellow...
- Milighetti M, Ceglia N, Patterson E, et al. (19 February 2025). "RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer". Nature:...
- (MHC) bounded peptides. They represent the antigenic determinants of neoantigens. Neoepitopes are recognized by the immune system as targets for T cells...
- mutations. These mutations potentially create new targetable antigens (neoantigens) for use in T-cell immunotherapy. The presence of CD8+ T cells in cancer...
- peptides. A requirement for the recognition of neoantigens by the immune system is that the neoantigens and their antigenic determinants, the neoepitopes...
- products currently in clinical development. Its lead product TG4050, a neoantigen individualized therapeutic cancer vaccine is currently being developed...