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Nectins and
Nectin-like
molecules (Necl) are
families of
cellular adhesion molecules involved in Ca2+-independent
cellular adhesion.
Nectins are ubiquitously...
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Nectin-3, also
known as
nectin cell
adhesion molecule 3, is a
protein that in
humans is
encoded by the NECTIN3 gene.
Nectin-3
belongs to the
family of...
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Poliovirus receptor-related 2 (PVRL2), also
known as
nectin-2 and CD112 (formerly
herpesvirus entry mediator B, HVEB), is a
human plasma membrane glycoprotein...
- cell
adhesion molecule Nectin-4. For wild type and
vaccine strains,
extracellular domains of CD150 (SLAM or SLAMF1) and/or of
nectin-4 (also called...
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Poliovirus receptor-related 1 (PVRL1), also
known as
nectin-1 and CD111 (formerly
herpesvirus entry mediator C, HVEC) is a
human protein of the immunoglobulin...
- antibody-drug
conjugate used for the
treatment of
urothelial cancer. It is a
nectin-4-directed
antibody and
microtubule inhibitor conjugate.
Enfortumab refers...
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mediates cellular adhesion to
other cells bearing its ligands,
nectin molecule CD112 and
nectin-like
protein CD155, that are
broadly distributed on normal...
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receptors include herpesvirus entry mediator (HVEM),
nectin-1 and 3-O
sulfated heparan sulfate. The
nectin receptors usually produce cell-cell adhesion, to...
- leukemias:
evidence for the
involvement of the
Poliovirus receptor (CD155) and
Nectin-2 (CD112)". Blood. 105 (5): 2066–73. doi:10.1182/blood-2004-09-3548. PMID 15536144...
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found on
immune cells like B or T cells, and antigen-presenting cells, or
nectin-4, a
cellular adhesion molecule. Once bound, the fusion, or F
protein helps...