- β-
Naltrexamine, or 6β-
naltrexamine, is an
opioid receptor antagonist related to
naltrexol and naltrexone. It has
served as a
parent pharmacop**** for irreversible...
-
Nalorphine Naltrexone Naltriben Naltrindole 6β-Naltrexol-d4 3-Iodobenzoyl
Naltrexamine Morphinan dimers Pseudomorphine Naloxo****ne
Norbinaltorphimine Somniferine...
-
bound to the same channel. 6α-naltrexo, 6β-naltrexol, 6β-naloxol, and 6β-
naltrexamine acted neutral antagonists regardless of
opioid binding and
caused significantly...
- "Narcotic
antagonistic potency of
bivalent ligands which contain beta-
naltrexamine.
Evidence for
bridging between proximal recognition sites".
Journal of...
- IBNtxA, or 3-iodobenzoyl
naltrexamine, is an
atypical opioid analgesic drug
derived from naltrexone. In
animal studies it
produces potent analgesic effects...
- MD,
Kalyuzhny AE,
Roerig SC,
Portoghese PS (2011). "N-naphthoyl-beta-
naltrexamine (NNTA), a
highly selective and
potent activator of μ/kappa-opioid heteromers"...
- "Narcotic
antagonistic potency of
bivalent ligands which contain .beta.-
naltrexamine.
Evidence for
simultaneous occupation of
proximal recognition sites"...
-
antagonist of the MOR with no
significant opioid agonistic actions.
Naltrexamine β-Chlornaltrexamine β-Fuoxymorphamine
Manglik A,
Kruse AC,
Kobilka TS...
- but also
shows some
irreversible mixed agonist–antagonist activity.
Naltrexamine, an
opioid receptor antagonist and the
parent compound β-Funaltrexamine...
- N-2′-Indolylnaltrexamine (INTA) is an
opioid and
derivative of β-
naltrexamine. This
molecule is
loosely derived from the
classical opioid morphine. This...
