- concentration) 50–72 (EC50Tooltip Half-maximal
effective concentration) (rat)
NETTooltip Norepinephrine transporter 27,000–30,500 (Ki) 360–405 (IC50) 54–110 (EC50)...
-
DATTooltip Dopamine transporter (DRIsTooltip
Dopamine reuptake inhibitors)
NETTooltip Norepinephrine transporter (NRIsTooltip
Norepinephrine reuptake inhibitors)...
- (HNK) IC50 NAM Rat ERαTooltip
Estrogen receptor alpha 0.34 Ki ND
Human NETTooltip Norepinephrine transporter 82–291 IC50
Inhibitor Human DATTooltip Dopamine...
- 000 (Ki) >100,000 (IC50Tooltip half-maximal
inhibitory concentration)
NETTooltip Norepinephrine transporter 5,600–>30,000 (Ki) >100,000 (IC50) DATTooltip...
-
DATTooltip Dopamine transporter (DRIsTooltip
Dopamine reuptake inhibitors)
NETTooltip Norepinephrine transporter (NRIsTooltip
Norepinephrine reuptake inhibitors)...
- Site Ki (nM)
Species Ref
SERTTooltip Serotonin transporter 15.2
Human NETTooltip Norepinephrine transporter 1,440
Human DATTooltip Dopamine transporter...
-
Olanzapine Site Ki (nM)
Action Ref
SERTTooltip Serotonin transporter 3676+ ND
NETTooltip Norepinephrine transporter 10000+ ND
DATTooltip Dopamine transporter 10000+...
- MK-801/PCPTooltip
phencyclidine site
SERTTooltip Serotonin transporter and
NETTooltip norepinephrine transporter blocker (cf. serotonin–norepinephrine reuptake...
- 662–3,900 (IC50Tooltip half-maximal
inhibitory concentration) 561 (EC50)
NETTooltip Norepinephrine transporter 13,000 (Ki) 14,000 (IC50) >10,000 (EC50) DATTooltip...
- 1.8–2.6 μM 4.8 μM 6.4 μM 4.0 μM Ki Ki IC50a IC50a
Human Rat
Human Rat
NETTooltip Norepinephrine transporter >10 μM >92 μM 35.6 μM 136 μM Ki Ki IC50a IC50a...
