- (NAmPRTase or
NAMPT),
formerly known as pre-B-cell colony-enhancing
factor 1 (PBEF1) or
visfatin for its
extracellular form (e
NAMPT), is an
enzyme that...
- miR-34a
suppresses the gene
expression of
NAMPT,
which encodes nicotinamide phosphoribosyltransferase (
NAMPT), the rate-limiting
enzyme in the nicotinamide...
-
phosphoribosyltransferase (
NAMPT). In 2016 Imai
expanded his
hypothesis to "NAD
World 2.0",
which postulates that
extracellular NAMPT from
adipose tissue maintains...
- NAM-based
pathway involving the
enzyme Nicotinamide phosphoribosyltransferase (
NAMPT) and the
formation of
nicotinamide mononucleotide (NMN). In 2004, a previously...
- CLOCK-BMAL
dimer activates transcription of the
Nampt gene,
which codes for the
NAMPT protein.
NAMPT is part of a
series of
enzymatic reactions that covert...
-
impairments cause mitochondrial dysfunction by
attenuating PGC1α and the
NAMPT-NAD+ pathway".
Nucleic Acids Research. 50 (17): 9948–9965. doi:10.1093/nar/gkac741...
- with
Vacor is
caused by its
conversion to Vacor-mononucleotide (VMN) by
NAMPT and VMN's
subsequent activation of the
NADase SARM1. Vogel, R. P. (1982)...
- (
NAMPT), the rate-limiting
enzyme responsible for the
transformation of
nicotinamide into
nicotinamide adenine dinucleotide (NAD). By
activating NAMPT...
- NMN by
blocking the
action of
nicotinamide phosphoribosyl transferase (
NAMPT) This
inhibition suggests that NMNH may be more
effective than NMN in directly...
-
Differentiation by
Activating SIRT1
through AMPK-Mediated
Regulation of
Nampt. Dev Cell 2008, 14 (5), 661–673. https://doi.org/10.1016/j.devcel.2008.02...