-
Nicotinic acetylcholine receptors, or
nAChRs, are
receptor polypeptides that
respond to the
neurotransmitter acetylcholine.
Nicotinic receptors also respond...
- (
nAChRs). The
nAChR is
named for its
affinity for nicotine.
Examples include nicotine (by definition),
acetylcholine (the
endogenous agonist of
nAChRs)...
- addiction. The MHb
shows a high
level of
nicotinic acetylcholine receptors (
nAChRs), that are
involved in many
forms of addiction.
Previously their expression...
-
receptors (
nAChRs) α4β2, α3β4, and α6β4, and chicken/mouse
nAChRs α7/5-HT3 in
certain areas of the brain. By
binding to the
allosteric site of the
nAChRs, a conformational...
-
receptors (
nAChRs), the kappa-bungarotoxin
family with
neuronal nAChRs, and
muscarinic toxins with
muscarinic acetylcholine receptors (mACh
Rs). The three-finger...
- they are
antagonists of post-synaptic
nicotinic acetylcholine receptors (
nAChRs) in the
neuromuscular synapse that bind
competitively and irreversibly,...
- (+)-Catharanthine
competitively inhibits α9α10
nAChRs with
potencies higher than that at α3β4 and α4β2
nAChRs and
directly blocks CaV2.2.
Catharanthine alkaloids...
-
receptor to
respond to
different stimuli. In the VB,
nAChRs can
contain the
subunits α4, α5, α7, and β2.
nAChRs that are made up of (α4β2)2α5 are of interest...
-
receptors (
nAChRs) is
about 100
times lower than nicotine's. Some work
suggests that
cotinine may be a
positive allosteric modulator of α7
nAChRs. If this...
-
believed to be act via
antagonism of
nicotinic acetylcholine receptors (
nAchRs). However, it also
appears to be a
competitive antagonist of
GABAA and glycine...
