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Myriocin, also
known as
antibiotic ISP-1 and thermozymocidin, is a non-proteinogenic
amino acid
derived from the
entomopathogenic fungus,
Isaria sinclairii...
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fungus mostly infecting the
underground nymphs of cicadas. It
produces myriocin, from
which the
synthetic drug fingolimod, a
treatment for
multiple sclerosis...
-
derived from an
immunosuppressive natural product,
myriocin (ISP-I)
through chemical modification.
Myriocin was
isolated from the
culture broth a type of entomopathogenic...
-
immunosuppressive action in ISP-1 (
myriocin), a
natural product derived from the
fungus Isaria sinclairii.
Myriocin, see
illustration 1, is an untraditional...
- exposure, and
biological aging.
Inhibition of
ceramide synthesis with
myriocin in
obese mice may lead to both
improved leptin signaling and decreased...
- In this respect, it
differs from all
other known immunosuppressants.
Myriocin has been
reported being 10 to 100
times more
potent than Ciclosporin. Immunosuppressive...
- galactomannan, adenosine, uridine, inosine, guanosine, cyclopeptides,
myriocin, and
inorganic elements. Li ZZ, Luan FG, Hywel-Jones NL,
Zhang SL, Chen...
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SPTTooltip Serine C-palmitoyltransferase
Myriocin Ceramidase Ceranib 1 OEA
SphKTooltip Sphingosine kinase N,N-DMS
Safingol SKI II...
-
causes an
elevation in ceramides.
Reducing ceramides with drugs,
including myriocin or desipramine,
alleviates lysosomal stress and
suppresses neurodegeneration...
-
SPTTooltip Serine C-palmitoyltransferase
Myriocin Ceramidase Ceranib 1 OEA
SphKTooltip Sphingosine kinase N,N-DMS
Safingol SKI II...
