-
Myostatin (also
known as
growth differentiation factor 8,
abbreviated GDF8) is a
protein that in
humans is
encoded by the MSTN gene.
Myostatin is a myokine...
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Myostatin-related
muscle hypertrophy is a rare
genetic condition characterized by
reduced body fat and
increased skeletal muscle size.
Affected individuals...
-
Myostatin inhibitors are a
class of
drugs that work by
blocking the
effect of
myostatin,
which inhibits muscle growth. In
animal models and
limited human...
- double-muscling
phenotype is a
heritable condition caused by a
deletion in the
myostatin gene,
resulting in an
increased number of
muscle fibres (hyperplasia)...
- the term
myokine first occurred in 2003. In 2008, the
first myokine,
myostatin, was identified. The gp130
receptor cytokine IL-6 (Interleukin 6) was...
-
known mutations that
limits and
reduces the
activity of the
myostatin protein. Normally,
myostatin limits the
number of
muscle fibers present at birth, and...
-
identified a
natural variant of the
myostatin gene
found in
Limousins which has a
significant influence on them. The
myostatin gene is
found in all
mammals and...
- injury/inflammation in
response to stress) are
increased in
sarcopenic obesity.
Myostatin is also increased. In the fat,
lipotoxicity and
chronic inflammation are...
- PMIDĀ 23995658. Lee SJ,
Gharbi A, Shin JE, Jung ID, Park YM (March 2021). "
Myostatin inhibitor YK11 as a
preventative health supplement for
bacterial sepsis"...
-
Piedmontese cattle carry a
unique gene
mutation identified as an
inactive myostatin allele that
causes hypertrophic muscle growth, or
double muscling. Purebred...