-
enzyme that
catalyzes the
chemical reaction 2 alpha,alpha-trehalose 6-
mycolate ⇌ {\displaystyle \rightleftharpoons } alpha,alpha-trehalose + alpha,alpha-trehalose...
- on the
outer membrane (diderm-LPS) and
those with
mycolic acid (diderm-
mycolate). The
export pathway is
responsible for
crossing the
inner cell membrane...
-
inside macrophages,
effectively hiding it from the host
immune system.
Mycolate biosynthesis is
crucial for
survival and
pathogenesis of M. tuberculosis...
-
species of
mycobacteria can be
potentiated by
isoniazid (through
inhibiting mycolate synthesis) and
ambroxol (through host
directed effects in
autophagy and...
-
characteristics Differentiation from all
other mycobacterial species by its
unusual mycolate pattern. Not ****ociated with disease.
Biosafety level 1
First isolated...
-
phylogenetic tree.
Embley MT,
Smida J,
Stackebrandt E (1988). "The
phylogeny of
mycolate-less wall
chemotype IV
Actinomycetes and
description of Pseudonocardiaceae...
- bacteria, is a
representative of this group. In addition,
Mycobacterium O-
mycolate proteins destined for the
outer membrane. The
plant chloroplast is capable...
- Furthermore, this
capsule inhibits entry of antibiotics. The
enzymes involved in
mycolate biosynthesis are
essential for
survival and pathogenesis, and thus represent...
-
glycolipids that can
signal through Mincle.
These include glucose and
trehalose mycolates, and
their closely related corynomycolates from
mycobacteria and corynebacteria...
-
Mycobacterium bovis bacillus Calmette-Guérin is due prin****lly to
trehalose mycolates".
Journal of Immunology. 174 (8): 5007–15. doi:10.4049/jimmunol.174.8...
