-
Motexafin lutetium is a texaphyrin,
marketed as
Antrin by
Pharmacyclics Inc. It is a
photosensitiser for use in
photodynamic therapy to
treat skin conditions...
- (INN)
motapizone (INN)
motavizumab (INN)
motesanib (USAN)
motexafin gadolinium (USAN)
motexafin lutetium (USAN)
Motofen motrazepam (INN)
motretinide (INN)...
-
Motexafin gadolinium (proposed
tradename Xcytrin) is an
inhibitor of
thioredoxin reductase and
ribonucleotide reductase. It has been
proposed as a possible...
-
university to
develop commercial and
medical uses for the molecules.
Motexafin lutetium is a texaphyrin,
marketed as
Antrin by
Pharmacyclics Inc. It...
-
treat cancer, infections, and
other diseases. The
drugs hydroxyurea and
Motexafin gadolinium interfere with the
action of this enzyme.
Hofer A,
Crona M...
-
several types of cancer,
including malignant mesothelioma. For example,
motexafin gadolinium (MGd) is a new
chemotherapeutic agent that
selectively targets...
-
clinical trials for the
treatment of
cancers include Photofrin, Temoporfin,
Motexafin lutetium,
Palladium bacteriopheophorbide, Purlytin, and Talaporfin. Verteporfin...
-
radiosensitisers (Xcytrin) and chemosensitisers. Xcytrin, a
gadolinium texaphyrin (
motexafin gadolinium), has been
evaluated in
Phase III
clinical trials against brain...
-
increase cellular ROS
stress level,
either by
direct ROS-generation (e.g.
motexafin gadolinium, elesclomol) or by
agents that
abrogate the
inherent antioxidant...
-
formation of
deoxyribonucleotides (building
blocks of DNA).
Examples include:
motexafin gadolinium.
hydroxyurea fludarabine, cladribine, gemcitabine, tezacitabine...
