-
Monoblasts are the
committed progenitor cells that
differentiated from a
committed macrophage or
dendritic cell
precursor (MDP) in the
process of hematopoiesis...
- Progenitor=progenitor cell, L-blast=lymphoblast, lymphocyte, Mo-blast=
monoblast, monocyte, myeloblast, Pro-M=promyelocyte, myelocyte, Meta-M=metamyelocyte...
- A
promonocyte (or premonocyte) is a cell
arising from a
monoblast and
developing into a monocyte.
Pluripotential hemopoietic stem cell
Hematopoiesis Schematic...
- body.
Monocytes are
produced by the bone
marrow from
precursors called monoblasts,
bipotent cells that
differentiated from
hematopoietic stem cells. Monocytes...
- Progenitor=Progenitor cell, L-blast=Lymphoblast, Lymphocyte, Mo-blast=
Monoblast, Monocyte, Myeloblast, Pro-M=Promyelocyte, Myelocyte, Meta-M=Metamyelocyte...
- are
predominantly monoblasts (>80%) (acute
monoblastic leukemia) or a
mixture of
monoblasts and
promonocytes (<80% blasts).
Monoblasts can be distinguished...
-
distinguish it from the
other "-blast"
cells (lymphoblast, myeloblast,
monoblast, and megakaryoblast). The
cytoplasm is blue in an H&E stain, indicating...
-
thrombocytopoiesis [root]blast
Lymphoblast Proerythroblast Myeloblast Monoblast Megakaryoblast pro[root]cyte
Prolymphocyte Polychromatophilic erythrocyte...
-
becoming a
mature eosinophil, basophil, or neutrophil.
Macrophages come from
monoblast progenitors that
differentiate into promonocytes,
which mature into monocytes...
- myeloblasts,
monoblasts and
promonocytes are <5% of
peripheral blood and <10% of bone marrow. CMML-2 is
diagnosed if: Myeloblasts,
monoblasts or promonocytes...
