-
membrane fusion complex,
Mitofusin 1 (Mfn1)/Mfn2/Optical
Atrophy Protein 1 (OPA1) complex. This
subfamily includes mitofusins 1 and 2. Mfn1 and Mfn2 (TC#...
-
Mitofusin-2 is a
protein that in
humans is
encoded by the MFN2 gene.
Mitofusins are
GTPases embedded in the
outer membrane of the mitochondria. In mammals...
- mitochondrial-resident
mitofusins form
heterocomplexes that
regulate the
number of inter-organelle
contact sites,
although mitofusins were
first identified...
-
level of the
outer mitochondrial membrane is
mediated by Mfn1 and Mfn2 (
Mitofusins 1 and 2), and
fusion at the
level of the
inner mitochondrial membrane...
-
mitochondrial transport in the
pathogenesis of Charcot-Marie-Tooth
disease from
mitofusin 2 mutations". The
Journal of Neuroscience. 27 (2): 422–430. doi:10.1523/JNEUROSCI...
- D, Lombès A (2003). "Membrane
topology and
mitochondrial targeting of
mitofusins,
ubiquitous mammalian homologs of the
transmembrane GTPase Fzo". J. Cell...
-
ubiquitination in a self-reinforcing cycle.
Parkin substrates include mitofusins Mfn1 and Mfn2,
which are
large GTPases that
promote mitochondria fusion...
- UCP;
nuclear factor erythroid 2 like 2, NFE2L2) and a
dynamics gene (
mitofusin 1, MFN1) were
upregulated (P < 0.05) at a low dose of NPY,
while a high...
-
includes classical dynamins, dynamin-like proteins, Mx proteins, OPA1,
mitofusins, and GBPs.
Members of the
dynamin family are prin****lly
involved in the...
- MIB2 (1p36) MIER1 (1p31) MIGA1:
encoding protein Mitoguardin 1 MFN2:
mitofusin 2 MFSD2:
Major facilitator superfamily domain containing 2A MIR6079: microRNA...
