-
Mitofusin-2 is a
protein that in
humans is
encoded by the MFN2 gene.
Mitofusins are
GTPases embedded in the
outer membrane of the mitochondria. In mammals...
- also
control mitochondrial fission.
These groups of
proteins include mitofusins, OPA1/Mgm1, and Drp1/Dnm1. All of
these molecules are GTP hydrolyzing...
-
mitochondrial transport in the
pathogenesis of Charcot-Marie-Tooth
disease from
mitofusin 2 mutations". The
Journal of Neuroscience. 27 (2): 422–430. doi:10.1523/JNEUROSCI...
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Mitofusin-1 is a
protein that in
humans is
encoded by the MFN1 gene. The
protein encoded by this gene is a
mediator of
mitochondrial fusion. This protein...
- to an
identified protein substrate. MARCH5 was
firstly identified as a
mitofusin 2- and Drp1-binding protein. MARCH5
promotes ubiquitination of Drp1 and...
- mitochondrial-resident
mitofusins form
heterocomplexes that
regulate the
number of inter-organelle
contact sites,
although mitofusins were
first identified...
- UCP;
nuclear factor erythroid 2 like 2, NFE2L2) and a
dynamics gene (
mitofusin 1, MFN1) were
upregulated (P < 0.05) at a low dose of NPY,
while a high...
- MIB2 (1p36) MIER1 (1p31) MIGA1:
encoding protein Mitoguardin 1 MFN2:
mitofusin 2 MFSD2:
Major facilitator superfamily domain containing 2A MIR6079: microRNA...
- with
mitofusin.
According to one model,
damaged mitochondria are
sequestered from
healthy mitochondria by the
degradation of Miro and
mitofusin. Miro...
-
Pinho CM,
Filadi R,
Wiehager B, Karlström H, et al. (September 2016). "
Mitofusin-2
knockdown increases ER-mitochondria
contact and
decreases amyloid β-peptide...
