- to the
large importance of the
skeleton in survival. Few deviations,
misregulations, and
mutations are
found in
organisms because they are
often detrimental...
- in epithelia,
positive T-cell selection, and CD8 T-cell activation.
Misregulation of
CaMKII is
linked to Alzheimer's disease,
Angelman syndrome, and heart...
- histones, and
chromatin remodelling).
Ageing and
disease are
related to a
misregulation of gene
expression through impaired methylation patterns, from hypomethylation...
- gene silencing. The
disorganization in
telomeres may have led to the
misregulation of ****ual development. Moreover, the
discovery of
specific transcription...
-
including cyclins, CDKs,
checkpoint regulators, and DNA
repair proteins.
Misregulation of the E2F
family is
often found in
cancer cases,
providing evidence...
- Lee TI,
Young RA (March 2013). "Transcriptional
regulation and its
misregulation in disease". Cell. 152 (6): 1237–1251. doi:10.1016/j.cell.2013.02.014...
-
signalling in
pathological processes.
Cancerous disease often involves misregulation of the BMP
signalling system.
Absence of BMP
signalling is, for instance...
-
encoding for
connexin channels proteins in the epidermis,
leading to the
misregulation of
homeostasis in keratinocytes. One type is
characterized by generalized...
-
involving many
different elements, and
therefore have many
targets for
misregulation.
Mutations that
cause constitutive activation of the Wnt
signaling pathway...
- concentration),
caused by an
increase of
protein expression (through
misregulation) an
increase of
protein (mRNA) stability,
prolonging its
existence and...
