-
genetic cause of most
cases of the
cancer follicular lymphoma – the
misregulation of the gene Bcl-2.
Korsmeyer went on to
start his own
laboratory at...
-
including cyclins, CDKs,
checkpoint regulators, and DNA
repair proteins.
Misregulation of the E2F
family is
often found in
cancer cases,
providing evidence...
- in epithelia,
positive T-cell selection, and CD8 T-cell activation.
Misregulation of
CaMKII is
linked to Alzheimer's disease,
Angelman syndrome, and heart...
-
mislocalisation of heterochromatin,
which normally lie in
close proximity, or with, the
nuclear matrix,
nuclear blebbing and
misregulation of gene expression....
- gene
fusion happens in non-coding
sequence region, it can lead to the
misregulation of the
expression of a gene now
under the
control of the cis-regulatory...
-
signalling in
pathological processes.
Cancerous disease often involves misregulation of the BMP
signalling system.
Absence of BMP
signalling is, for instance...
- Young,
Richard A. (March 2013). "Transcriptional
Regulation and Its
Misregulation in Disease". Cell. 152 (6): 1237–1251. doi:10.1016/j.cell.2013.02.014...
- histones, and
chromatin remodelling).
Ageing and
disease are
related to a
misregulation of gene
expression through impaired methylation patterns, from hypomethylation...
- gene silencing. The
disorganization in
telomeres may have led to the
misregulation of ****ual development. Moreover, the
discovery of
specific transcription...
- such as anti-centromere antibodies. It has been
known that
centromere misregulation contributes to mis-segregation of chromosomes,
which is
strongly related...