-
thyroid disease, and obesity.
Endocrine disease is
characterized by
misregulated hormone release (a
productive pituitary adenoma),
inappropriate response...
- and cell survival. As such, many
different types of
human tumors have
misregulated NF-κB: that is, NF-κB is
constitutively active.
Active NF-κB
turns on...
-
important plasma cell differentiation-related genes, IRF4 and Blimp1, are
misregulated, and XBP1-lacking
plasma cells fail to
colonize their long-lived niches...
- muscle-specific
chloride channel in type 1
myotonic dystrophy due to
misregulated alternative splicing".
Molecular Cell. 10 (1): 45–53. doi:10.1016/s1097-2765(02)00572-5...
-
expressed in
cells of the
human innate immune system.
These enzymes, when
misregulated, are a
major source of
mutation in
numerous cancer types. When the expression...
- the cell
nucleus to the cytoplasm. CRM1 it is
often overexpressed and
misregulated in cancer, and is the sole
transporter of many
proteins essential for...
- disease. Many
cancers arise from the
inappropriate epigenetic effects of
misregulated methylation. However,
because these processes are at
times reversible...
- and
appropriate cytokine release will
result in
small white dots and a
misregulated response eventually will
produce scarring of the
retinal tissue. Treatment...
-
being investigated as a
method of
correcting the
expression levels of
misregulated genes in
neurodegenerative diseases.
Neurodengenerative diseases of motor...
-
nucleus to the cytoplasm; it is
often overexpressed and its
function misregulated in
several types of cancer. By
inhibiting the XPO1 protein,
SINEs lead...
