-
ordinarily must
recognize and
correctly repair a
small number of base
mispairs within a long
sequence of
normal DNA base pairs. To
repair mismatches formed...
- with MSH2 in
order to
correct long insertion/deletion
loops and base-base
mispairs in
microsatellites during DNA synthesis.
Deficient capacity for MMR is...
- and SMUG1 are the
major enzymes responsible for the
repair of the U:G
mispairs caused by
spontaneous cytosine deamination,
whereas uracil arising in DNA...
-
directed mismatch repair pathway (MMR)
actually fixes unnatural-natural
mispairs,
whereas recombinational repair actually cuts out the unnatural. The E...
-
oxidized nitrogeneous bases observed.
During DNA replication, DNA
polymerase mispairs 8-oxoguanine with adenine,
leading to a G→T
transversion mutation. The...
- 1016/0959-437X(95)80055-7. PMID 7549435.
Acharya S, et al. (1996). "hMSH2
forms specific mispair-binding
complexes with hMSH3 and hMSH6". PNAS. 93 (24): 13629–34. Bibcode:1996PNAS...
- base
pairing to
specific tRNA anticodons. Aminoacyl-tRNA
synthetases that
mispair tRNAs with the
wrong amino acids can
produce mischarged aminoacyl-tRNAs...
- 2010). "Functional
studies and
homology modeling of Msh2-Msh3
predict that
mispair recognition involves DNA
bending and
strand separation". Mol. Cell. Biol...
- 6-O-Methylguanines in DNA.
About one
third of the time 6-O-methylguanine
mispairs during replication,
leading to the
incorporation of dTMP
rather than dCMP...
-
releasing free uracil. This
enzyme is not
active on DNA
containing a T/G
mispair or single-stranded DNA.
Barrett TE, Schärer OD,
Savva R,
Brown T, Jiricny...
