-
incorporated into
proteins (like GABA, L-DOPA, or triiodothyronine),
misincorporated in
place of a
genetically encoded amino acid, or not
produced directly...
-
action of BMAA. More recently,
evidence has been
found that BMAA is
misincorporated in
place of L-serine in
human proteins. A
considerable portion of the...
-
Banack SA,
Rodgers KJ (2013). "The non-protein
amino acid BMAA is
misincorporated into
human proteins in
place of L-serine
causing protein misfolding...
-
oxidative stress in the
neuron by
depletion of glutathione. BMAA can be
misincorporated into
nascent proteins in
place of L-serine,
possibly causing protein...
-
synthesizing proteins has been
estimated to be
between 1 in 105 and 1 in 103
misincorporated amino acids,
depending on the
experimental conditions. The rate of...
- pair,
effectively changing a base and
introducing a mutation. This
misincorporated base will not be
corrected during DNA
replication as
thymine is a DNA...
-
RNase H2
gives it a role in
ribonucleotide excision repair,
removing misincorporated ribonucleotides from DNA, in
addition to R-loop processing. Although...
-
longer lifespan. RNASEH2 is emplo**** in
genome surveillance to
remove misincorporated ribonucleotides in DNA. In mice, the loss of RNASEH2
activity causes...
-
polymerase performs two
known proof reading functions to
detect and
remove misincorporated nucleotides:
pyrophosphorylytic editing and
hydrolytic editing. The...
-
monophosphate (dUMP),
which increases the
likelihood that
uracil gets
misincorporated into the DNA. Also,
subsequent phosphorylations of TF-TMP
cause an...
