-
incorporated into
proteins (like GABA, L-DOPA, or triiodothyronine),
misincorporated in
place of a
genetically encoded amino acid, or not
produced directly...
-
action of BMAA. More recently,
evidence has been
found that BMAA is
misincorporated in
place of L-serine in
human proteins. A
considerable portion of the...
-
Banack SA,
Rodgers KJ (2013). "The non-protein
amino acid BMAA is
misincorporated into
human proteins in
place of L-serine
causing protein misfolding...
-
oxidative stress in the
neuron by
depletion of glutathione. BMAA can be
misincorporated into
nascent proteins in
place of L-serine,
possibly causing protein...
-
synthesizing proteins has been
estimated to be
between 1 in 105 and 1 in 103
misincorporated amino acids,
depending on the
experimental conditions. The rate of...
- pair,
effectively changing a base and
introducing a mutation. This
misincorporated base will not be
corrected during DNA
replication as
thymine is a DNA...
-
polymerase performs two
known proof reading functions to
detect and
remove misincorporated nucleotides:
pyrophosphorylytic editing and
hydrolytic editing. The...
- to 3' end, the
exonuclease activity immediately removes nucleotides misincorporated at the 3' end of the
growing DNA strand. Consequently, Pfu DNA polymerase-generated...
- and meteorites). Some
natural amino acids, such as norleucine, are
misincorporated translationally into
proteins due to
infidelity of the protein-synthesis...
-
These repair processes include (1)
removal of
misincorporated bases; (2)
removal of
misincorporated ribonucleotides; (3)
removal of
damaged bases (e...
