-
monitor neuronal functions through direct somatic contacts via
their microglial processes, and
exert neuroprotective effects when needed. The
brain and...
- differentiate.
These cells are
found in all
regions of the
brain and
spinal cord.
Microglial cells are
small relative to
macroglial cells, with
changing shapes and...
-
cellular morphology,
specifically the
enlargement of
cellular processes. The
microglial immunological surface receptor CR3 is also
upregulated within 24 hours...
- hyperthermia,
increasing dopamine synthesis and release,
influencing microglial activation, and
modulating apoptotic signaling cascades and the formation...
- and
microglial activation has been do****ented in
those with mild
cognitive impairment,
despite a lack of
tracer uptake,
suggesting that
microglial dysfunction...
-
infect a
variety of
immune cells such as CD4+ T cells, macrophages, and
microglial cells. HIV-1
entry to
macrophages and CD4+ T
cells is
mediated through...
- of
myelin sheaths. It is
believed that the
disease arises from
primary microglial dysfunction that
leads to
secondary disruption of
axonal integrity, neuroaxonal...
- to
further alpha-synuclein ac****ulation in a
positive feedback loop.
Microglial activation,
possibly caused by alpha-synuclein, is also
strongly indicated...
-
necessary for
physiological and
pathological microglial actions, such as
monitoring neuronal functions and
microglial neuroprotection. The
drugs clopidogrel...
-
neurodegenerative disorders,
including Alzheimer's disease. TREM2 is
involved in the
microglial response to the
amyloid plaques that are
characteristic of AD. Loss of...
