-
monitor neuronal functions through direct somatic contacts via
their microglial processes, and
exert neuroprotective effects when needed. The
brain and...
-
cellular morphology,
specifically the
enlargement of
cellular processes. The
microglial immunological surface receptor CR3 is also
upregulated within 24 hours...
-
neurodegenerative disorders,
including Alzheimer's disease. TREM2 is
involved in the
microglial response to the
amyloid plaques that are
characteristic of AD. Loss of...
-
intravital microscopy studies. For example, in
order to
study the
behavior of
microglial cells in Alzheimer's
disease researchers will need to
crossbreed a transgenic...
- and
microglial activation has been do****ented in
those with mild
cognitive impairment,
despite a lack of
tracer uptake,
suggesting that
microglial dysfunction...
- hyperthermia,
increasing dopamine synthesis and release,
influencing microglial activation, and
modulating apoptotic signaling cascades and the formation...
- Furthermore, tissue-injury
induced ATP-signalling is a
major factor in
rapid microglial phenotype changes. ATP
fuels muscle contractions.
Muscle contractions...
- In JE the
tight regulation of
microglial activation appears to be disturbed,
resulting in an
autotoxic loop of
microglial activation that
possibly leads...
- to
further alpha-synuclein ac****ulation in a
positive feedback loop.
Microglial activation,
possibly caused by alpha-synuclein, is also
strongly indicated...
-
infect a
variety of
immune cells such as CD4+ T cells, macrophages, and
microglial cells. HIV-1
entry to
macrophages and CD4+ T
cells is
mediated through...
