- halogen-magnesium exchange: fast, homogeneous: XC6H4Br + i−Pr
MgCl·Li
Cl → XC6H4Mg
Cl·Li
Cl + i−Pr
Cl +
MgBrCl The
traditional method for
generating the aryl Grignard...
- PbCl2 + 4 RLi → R4Pb + 4 Li
Cl + Pb 2 PbCl2 + 4 RMg
Br → R4Pb + Pb + 4
MgBrCl 3 PbCl2 + 6 RMg
Br → R3Pb-PbR3 + Pb + 6
MgBrCl These reactions produce derivatives...
-
Illustrative is
preparation of tris(pentafluorophenyl)borane: 3 C6F5Mg
Br + BCl3 → (C6F5)3B + 3
MgBrCl Other derivatives include LiB(C6F5)4, [CuC6F5]4, and Ni(C6F5)2(dioxane)2...
- (sometimes
called phosphanes) such as triphenylphosphine, Ph3P. 3 RMg
Br + PCl3 → R3P + 3
MgBrCl Triphenylphosphine is
produced industrially by the
reaction between...
- iron(III) chloride,
resulting in ferrocene: 3 C5H5Mg
Br + FeCl3 → Fe(C5H5)2 + 1/n (C5H5)n + 3
MgBrCl This conversion,
although not of
practical value, was...
-
tetraaryltin compounds can be
prepared using Grignard reagents: Sn
Cl 4 + 4 RMg
Br → R 4Sn + 4
MgBrCl The
mixed halide-alkyls,
which are more
common and more important...
-
Grignard reagent formed from
mesityl bromide: 2 FeCl2 + 4
BrMgC6H2(CH3)3 → Fe2(C6H2(CH3)3)4 + 2
MgBrCl Müller, Hardy; Seidel, Wolfgang; Görls,
Helmar (1993)...
- acid workup: (C2H5O)2P(O)H + 3 C6H5Mg
Br → (C6H5)2P(O)
MgBr + C2H5OMg
Br (C6H5)2P(O)
MgBr + HCl → (C6H5)2P(O)H +
MgBrCl Alternatively, it may be
prepared by...
-
formula R−
Mg−X,
where X is a
halogen and R is an
organic group,
normally an
alkyl or aryl. Two
typical examples are
methylmagnesium chloride Cl−
Mg−CH3 and...
- by the
synthesis of dibutyldivinyltin: Bu2SnCl2 + 2 CH2=CHMg
Br → Bu2Sn(CH=CH2)2 + 2
MgBrCl The
organotin hydrides are
generated by
reduction of the mixed...
