- of adenosine, and
increase alertness in the
central nervous system.
Methylxanthines (methylated xanthines),
which include caffeine, aminophylline, IBMX...
- 7-
Methylxanthine (7-MX), also
known as heteroxanthine, is an
active metabolite of
caffeine (1,3,7-trimethylxanthine) and
theobromine (3,7-dimethylxanthine)...
- IBMX (3-isobutyl-1-
methylxanthine), like
other methylxanthine derivatives, is both a:
competitive non-selective
phosphodiesterase inhibitor which raises...
-
Caffeine is a
central nervous system (CNS)
stimulant of the
methylxanthine class and is the most
commonly consumed psychoactive substance globally. It...
-
Related compounds include theophylline, caffeine, paraxanthine, and 7-
methylxanthine, each of
which differ in the
number or
placement of the
methyl groups...
-
inhaled glucocorticoids, long-acting
muscarinic antagonists (LAMA),
methylxanthines/phosphodiesterase inhibitors,
leukotriene receptor antagonists, mast...
-
pulmonary disease (COPD) and asthma. Its
pharmacology is
similar to
other methylxanthine drugs (e.g.,
theobromine and caffeine).
Trace amounts of theophylline...
-
enzyme that
catalyzes the
chemical reaction S-adenosyl-L-methionine + 7-
methylxanthine ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + 3...
- of caffeine.
After formation,
paraxanthine can be
broken down to 7-
methylxanthine by
demethylation of the N1 position,
which is
subsequently demethylated...
- 7-
Methylxanthine demethylase (EC 1.14.13.128) is an
enzyme with
systematic name 7-
methylxanthine:oxygen
oxidoreductase (demethylating). This
enzyme catalyses...