- also
known as L-5-MTHF, L-methylfolate and L-5-
methyltetrahydrofolate and (6S)-5-
methyltetrahydrofolate, and (6S)-5-MTHF) is the
primary biologically active...
-
catalyzes the
conversion of 5,10-methylenetetrahydrofolate to 5-
methyltetrahydrofolate, a
cosubstrate for
homocysteine remethylation to methionine. Natural...
- in most individuals. In
humans it is
encoded by the MTR gene (5-
methyltetrahydrofolate-homocysteine methyltransferase).
Methionine synthase forms part...
-
intermediate in one-carbon metabolism, 5,10-CH2-THF
converts to 5-
methyltetrahydrofolate, 5-formyltetrahydrofolate, and methenyltetrahydrofolate. It is substrate...
- 5-
methyltetrahydrofolate:corrinoid/iron-sulfur
protein Co-methyltransferase (EC 2.1.1.258, acsE (gene)) is an
enzyme with
systematic name...
- and 5-
methyltetrahydrofolate are
needed by
methionine synthase in the
methionine cycle to
transfer a
methyl group from 5-
methyltetrahydrofolate to homocysteine...
-
related compounds,
including tetrahydrofolic acid (the
active form),
methyltetrahydrofolate (the
primary form
found in blood), methenyltetrahydrofolate, folinic...
- (EC 1.5.7.1) is an
enzyme that
catalyzes the
chemical reaction 5-
methyltetrahydrofolate + 2
oxidized ferredoxin ⇌ {\displaystyle \rightleftharpoons } 5...
-
cancer treatment.
Cerebral folate deficiency is when
levels of 5-
methyltetrahydrofolate are low in the
brain as
measured in the
cerebral spinal fluid despite...
-
recycled back to
methionine through transfer of a
methyl group from 5-
methyltetrahydrofolate, by one of the two
classes of
methionine synthases (i.e. cobalamin-dependent...
