-
Methylmalonyl-CoA is the
thioester consisting of
coenzyme A
linked to
methylmalonic acid. It is an
important intermediate in the
biosynthesis of succinyl-CoA...
-
Methylmalonyl-CoA
mutase (EC 5.4.99.2, MCM), mitochondrial, also
known as
methylmalonyl-CoA isomerase, is a
protein that in
humans is
encoded by the MUT...
- beta-oxidation. Propionyl-CoA is
carboxylated to D-
methylmalonyl-CoA,
isomerized to L-
methylmalonyl-CoA, and
rearranged to
yield succinyl-CoA via a vitamin...
- acidemias.
Methylmalonyl-CoA
requires vitamin B12 to form succinyl-CoA. When the
amount of B12 is
insufficient for the
conversion of
cofactor methylmalonyl-CoA...
-
Methylmalonyl-CoA
mutase is a
mitochondrial homodimer apoenzyme (EC. 5. 4.99.2) that
focuses on the
catalysis of
methylmalonyl CoA to
succinyl CoA. The...
- is
converted into D-
methylmalonyl-CoA by propionyl-CoA
carboxylase and then
converted into L-
methylmalonyl-CoA by
methylmalonyl-CoA epimerase. Entry...
-
cofactor in
methylmalonyl-CoA mutase—MUT enzyme.
Processing of
cholesterol and
protein gives propionyl-CoA that is
converted to
methylmalonyl-CoA, which...
-
Methylmalonyl CoA
epimerase (EC 5.1.99.1,
methylmalonyl-CoA racemase,
methylmalonyl coenzyme A racemase, DL-
methylmalonyl-CoA racemase, 2-methyl-3-oxopropanoyl-CoA...
- enzymes:
Methylmalonyl coenzyme A
mutase (MUT) is an
isomerase enzyme which uses the AdoB12 form and
reaction type 1 to
convert L-
methylmalonyl-CoA to succinyl-CoA...
- The
enzyme (S)-
methylmalonyl-CoA
hydrolase (EC 3.1.2.17)
catalyzes the
reaction (S)-
methylmalonyl-CoA + H2O ⇌ {\displaystyle \rightleftharpoons } methylmalonate...
