- The
enzyme methylisocitrate lyase (EC 4.1.3.30)
catalyzes the
chemical reaction (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate ⇌ {\displaystyle \rightleftharpoons...
- The
enzyme 2-
methylisocitrate dehydratase (EC 4.2.1.99)
catalyzes the
chemical reaction (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate ⇌ {\displaystyle \rightleftharpoons...
- (MCS) in step one,
methylcitrate dehydratase (MCD) in step two, and 2-
methylisocitrate lyase (MCL) in step three. The PrpC gene,
which encodes for enzyme...
- EC 4.1.3.29: Now EC 2.3.3.4,
decylhomocitrate synthase EC 4.1.3.30:
methylisocitrate lyase EC 4.1.3.31: Now EC 2.3.3.5, 2-methylcitrate
synthase EC 4.1...
- tuberculosis, ICL
isoforms 1 and 2 also play the role of
methylisocitrate lyase,
converting methylisocitrate into
succinate and pyruvate. This is
important because...
-
phosphinothricin tripeptide antibiotics.
Isocitrate lyase InterPro: IPR006254
Methylisocitrate lyase InterPro: IPR012695 Carboxyvinyl-carboxyphosphonate phosphorylmutase...
- open conformation). The
structure of
PEPPM is very
similar to that of
methylisocitrate lyase, an
enzyme involved in
propanoate metabolism whose substrate...
