- methylation. Thus,
mutations in IDH1 and IDH2
generate a "DNA CpG
island methylator phenotype or CIMP" that
causes promoter hypermethylation and concomitant...
-
important genetic abnormalities include BRAF mutations,
abnormal CpG
island methylator phenotype, and
microsatellite instability. However, most
individuals with...
-
Ahuja N,
Herman JG,
Weijenberg MP, van
Engeland M (2012). "The CpG
island methylator phenotype in
colorectal cancer:
Progress and problems".
Biochim Biophys...
- G.C.; Bartha, R. (1985-08-01). "Sulfate-Reducing Bacteria: Prin****l
Methylators of
Mercury in
Anoxic Estuarine Sediment".
Applied and
Environmental Microbiology...
-
Rashid A, Wu EF, et al. (August 2003). "****ociation of the CpG
island methylator phenotype with
family history of
cancer in
patients with
colorectal cancer"...
-
mercury can
occur abiotically or biotically. Biotically, the
primary methylators of
mercury are sulfate-reducing and iron-reducing bacteria.
Three mechanisms...
-
Compeau & R.
Bartha (August 1985), "Sulfate-Reducing Bacteria: Prin****l
Methylators of
Mercury in
Anoxic Estuarine Sediment",
Applied and
Environmental Microbiology...
- AW,
Beardsley DI, Kim WJ, Gao Y,
Baskaran R,
Brown KD (March 2005). "
Methylator-induced,
mismatch repair-dependent G2
arrest is
activated through Chk1...
-
research fellow twenty years ago
identified the
concept of CpG
island methylator phenotype (CIMP) or CpG
island hypermethylation in
colorectal cancer....
- It is
useful to
consider a
particular tumor type,
called CpG
island methylator phenotype, or CIMP:
higher levels of CpG
island hypermethylation are found...
