-
initiates the
neuronal excitation involves the
conversion of
metarhodopsin I to
metarhodopsin II,
which is ****ociated with
deprotonation of the Schiff's...
- configuration.
Opsin therefore undergoes a
conformational change to
metarhodopsin II.
Metarhodopsin II
activates a G
protein known as transducin. This
causes transducin...
- →
metarhodopsin II (i.e., 11-cis
photoisomerizes to all-trans): (rhodopsin + hν →
photorhodopsin →
bathorhodopsin →
lumirhodopsin →
metarhodopsin I →...
- →
metarhodopsin II (i.e., 11-cis
photoisomerizes to all-trans): (rhodopsin + hν →
photorhodopsin →
bathorhodopsin →
lumirhodopsin →
metarhodopsin I →...
- Rh
undergoes a
conformational change into its
active form,
metarhodopsin.
Metarhodopsin activates Gq,
which in turn
activates a
phospholipase Cβ (PLCβ)...
- all-trans.
Isomerization causes a
change in the
opsin to
become metarhodopsin II. When
metarhodopsin activates transducin, the
guanosine diphosphate (GDP) bound...
-
detection of light. The
opsin then
splits into the
protein component (such
metarhodopsin) and the
cofactor all-trans-retinal. The
regeneration of
active opsin...
-
calcium ion
influx after channel closing causes phosphorylation of
metarhodopsin II and
speeds up the cis-retinal to trans-retinal inactivation. The...
- by calcium-bound recoverin,
leading to a more
rapid inactivation of
metarhodopsin II (activated form of rhodopsin).
Recoverin structure consists of four...
-
Morizumi T, Pai EF,
Krauss N, et al. (March 2011). "Crystal
structure of
metarhodopsin II". Nature. 471 (7340): 651–655. Bibcode:2011Natur.471..651C. doi:10...
